[Pathophysiology of tremor rhythm].
نویسنده
چکیده
Tremor is a rhythmic involuntary movement of any body parts. Some peripheral and central mechanisms can produce it. The former includes peripheral mechanical oscillations and oscillations due to spinal reflexes. The latter includes central oscillations originated from some central pacemakers or network loops through cerebellum, basal ganglia or others.Weight loading on a body part is one method for differentiation between the peripheral and central mechanisms. In peripheral tremor, the weight load usually changes the tremor frequency. In contrast, it is not affected by the load in the central tremor. Both mechanisms relate to produce essential tremor and enhanced physiological tremor.Basal ganglia, sensory-motor cortex, cerebellum, red nucleus and inferior olive nucleus could be the central pacemakers or involved in the central loops for tremor.The facilitation and inhibition imbalance within a pacemaker or imbalance between feed-forward and feedback regulations within central loops may generate some rhythms.
منابع مشابه
Gene regulation network fitting of genes involved in the pathophysiology of fatty liver in the mice by promoter mining
Background and Aim: Non-Alcoholic Fatty Liver Disease (NAFLD) is the major cause of chronic liver disease in developed countries. In this study, we identified the most important transcription factors and biological mechanisms affecting the incidence of fatty liver disease using the promoter region data mining. Materials and Methods In this study, at first, the marker genes associated with this...
متن کاملInsights into Pathophysiology from Medication-induced Tremor
Background Medication-induced tremor (MIT) is common in clinical practice and there are many medications/drugs that can cause or exacerbate tremors. MIT typically occurs by enhancement of physiological tremor (EPT), but not all drugs cause tremor in this way. In this manuscript, we review how some common examples of MIT have informed us about the pathophysiology of tremor. Methods We performe...
متن کاملFinger tremor in tabetic patients and its bearing on the mechanism producing the rhythm of physiological tremor.
In a recent paper, Marshall and Walsh (1956) have considered various possible explanations of the tremor with a characteristic peak frequency of 8 to 10c./sec. which is associated with muscular contraction in healthy subjects. Among other theories, they consider but reject the hypothesis that tremor may be due to oscillation round the " servo-loop " from muscle spindle to muscle (Halliday and R...
متن کاملPathophysiology of nonparkinsonian tremors.
Patients with nonparkinsonian tremors are the second largest group treated with functional neurosurgery. We summarize the present pathophysiological knowledge of these conditions. Essential tremor (ET) may be due to oscillations within the olivocerebellar circuit. There is experimental evidence from animal models for such a mechanism, and clinical data indicate an abnormal function of the cereb...
متن کاملDiurnal variation of essential and physiological tremor.
Evaluations were made of the diurnal variations of tremor power at rest, after fatigue and after mass loading, and plasma norepinephrine in patients with familial essential tremor and normal subjects. Diurnal tremor power rhythms for both essential and physiological tremor pursued identical temporal profiles. Plasma norepinephrine levels followed a congruent diurnal pattern with later peak valu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Rinsho shinkeigaku = Clinical neurology
دوره 23 11 شماره
صفحات -
تاریخ انتشار 2013